Repeated protein domains

This is a plot of Drosophila melanogaster SLIT protein against itself. It has several repeated domains. In the N-terminal part (A), we see four repeated regions, which are themselves made up of smaller repeated units (in this case, leucine-rich repeats). Then, there is another domain that's repeated at least six times in a tight cluster (B), with one additional occurrence near the C-terminus. This one is an EGF.

repeats

The figure below shows the arrangement of the domains along the protein sequence, as described in the Swiss-Prot entry.

domains_map

Previous | Next | Top